Four Things You May Not Know About Salt Consumption

Monday, August 23, 2010 by Stephen Sinatra
If you’re working hard to prevent heart attack and stroke, as well as the occurrence of other cardiovascular problems, you need to beware of the dangers associated with salt. 

As any decent doctor or holistic practitioner will tell you, having too much salt in your system can make it difficult for you to maintain healthy blood pressure levels, as well as healthy cholesterol levels.  In fact, too much salt can severely compromise your overall health and force you to deal with a myriad of serious heart risk factors you’d do well to avoid.

Here are four things you may not know about salt consumption:
  1. Your body requires sodium (a component of salt) to regulate fluid balance and distribution, as well as nerve and muscle cell function. Although you need some sodium, the standard American diet includes way too much. That’s why I urge my patients to try what I often refer to as "the healthiest diet of all." You'll be amazed at how effective it can be.
  2. The current recommendation for salt consumption is less than 2,400 mg of sodium a day, which amounts to about one teaspoon of salt. Recent research suggests that people ingesting less than 1,500 mg of sodium a day are better able to keep their blood pressure low. If you have high blood pressure, you should definitely aim for that kind of level. Don’t use salt from the shaker, and read labels to add up the amount you’re taking in.
  3. Many items at fast food restaurants are high in salt, so you can easily exceed the recommended level with one serving.
  4. You can easily make up for the reduced salt in your diet by cooking with fresh herbs and spices such as basil, garlic, oregano, rosemary, chives, parsley, and onion. What’s more, all of these flavorings contain natural substances that are good for your health. Garlic, in particular, has been shown to have a positive effect on blood pressure when consumed on a daily basis.
I hope you'll share this information with your friends and loved ones. It's just another example of how you can do something simple to help control your cardiovascular health.

For more information on blood pressure levels and other cardiovascular problems, visit www.drsinatra.com.

Let Food Be Thy Medicine

Thursday, August 19, 2010 by Jan Sinatra
Dr. Sinatra has long believed in the famous words of Hippocrates, the Greek physician of centuries past who is now recognized as the “Father of Medicine.” Hippocrates employed food to assist his patients in healing their physical ailments. With all our high tech medical approaches and complex pharmaceutical agents, it is amazing how much we have forgotten that simple approach!

After years of applying nutritional solutions to the myriad faces of heart disease—high blood pressure levels; chronic hypertension; high triglycerides; elevated L(p)a; angina; and heart attack and stroke—Dr. Sinatra has finally answered his patients’ many requests for a book that they can have as a reference at home. His research and personal experiences with his family, friends, and cardiac patients has continually impressed my husband that Hippocrates was so right on—and provided the foundation for this effort.     

Dr. Sinatra has collaborated with former pro athlete and health editor Jim Healthy, as well as recipe queen Rebecca Bent to write Bottom Line’s The Healing Kitchen. The Healing Kitchen is a strategic resource for making healthy grocery selections and healing meal planning guidelines, as well as specific recipes to assist you in selecting the right healthy foods to meet your specific health and fitness needs.

Subscribers to Heart, Health, and Nutrition have been reading Dr. Sinatra’s take on which foods, herbs, and supplements can help with their cardiovascular problems (not to mention cancer and other diseases caused by inflammation) for many years. Now all that information and more is the basis for this one reference to help guide you to foods that can heal your body.

For instance, the omega 3 essential fatty acids—especially those found in squid and fish oils—assuage cardiac arrhythmia, lower blood pressure levels, reduce LDL cholesterol levels, and even prevent plaque rupture.

Garlic is a potent blood thinner and, like onions which are rich in quercetin, helps you prevent the oxidation of LDL cholesterol. Garlic and onions are both superb foods for lowering blood pressure levels. And, speaking of hypertension, Dr. Sinatra also recommends sardines and wakame seaweed as natural blood pressure lowering foods.

And that’s just the beginning! Did you know that the right diet can help alleviate your migraines headaches, or that non-inflammatory foods can heal your arthritis?

Foods can also protect women from menopausal symptoms, as well as heal and protect us from cancer. The lutein in tomatoes along with pumpkin seeds and other fine herbs and spices can help men with their prostate concerns. From heart disease and diabetes to sleep and sex, The Healing Kitchen will educate you about natural, tasty remedies for many of the illnesses that afflict the 20th century. 

If you are looking to use simple, healthy foods, herbs and spices to get your body back on track, and keep it there, you will love this book!

For more information on healthy heart nutrition or some of Dr. Sinatra’s famous recipes, visit his Web site at www.drsinatra.com.

Cardiovascular Problems and Women

Wednesday, August 18, 2010 by Stephen Sinatra
I worry about the fact that so many women still think that cardiovascular problems, like heart disease and stroke, is primarily a problem for men. The truth is that heart disease is a major health risk for women, but many physicians did not realize this until recently, so they’ve done little to encourage their female patients to take steps to protect their heart health.

I also worry because much of our knowledge about heart disease describes how the condition affects men. This leads many physicians, including some holistic practitioners, to diagnose and treat women as if heart disease affected them the same way. Nothing could be further from the truth. Heart disease affects men and women very differently and I’ve written about that here in this in newsletter articles, books, and here in this blog.

For example, if a 45-year-old woman and a 45-year-old man both come into the emergency room with chest pain, most physicians will probably admit the man and tell the woman her symptoms are due to stress and anxiety. Not many physicians realize that the incidence of coronary events among women quadruples as they reach middle age.

What You Can Do About It

I want you to understand that much of this, in both women and men, is related to lifestyle and the choices you make.
  • Choose to seek natural ways to lower blood pressure if that’s a problem for you.
  • Choose to adhere to good cardiovascular nutrition, which may include increasing the amount of fresh vegetables you consume and lowering the amount of breads and other starches you eat each day.
  • Choose to do what you need to do to maintain good cholesterol levels, improve blood circulation, and healthy triglycerides.
  • Choose to exercise so that you can more easily prevent blood clots and maintain a healthy weight.
In short, while it may be difficult at the start, choose to live a healthy lifestyle.  Choose life.

For more information on women and cardiovascular problems or tips for good cardiovascular nutrition, visit Dr. Sinatra's Web site.

Healthy Cholesterol Is Great, But...

Monday, August 16, 2010 by Stephen Sinatra
Though you wouldn’t know it based on today’s obsession with cholesterol levels, cardiology has been slowly veering away from the narrow view of cholesterol as a primary cause of coronary artery disease (CAD).

The field is finally realizing that although good cholesterol levels can help deter the biochemical process that creates damage in arterial walls—which in turn leads to plaque, occlusions, and clots—it’s a relatively minor one. In other words, they’ve realized that even though they may find cholesterol at the scene of the crime, it’s not necessarily the perpetrator.

An excellent example of this is shared in a population study that showed how the French have the highest total cholesterol levels in Europe—about 250—but the lowest incidence of cardiovascular problems, including heart disease.

This being said, I continue to encourage you to find natural ways to maintain healthy cholesterol, including adhering to a smart, cholesterol lowering diet.  I just want you to also realize that cholesterol is just one of many heart risk factors, and is not necessarily the most deadly.

For more information on reducing cholesterol and other cardiovascular problems, visit Dr. Sinatra's Web site.

Four Common Heart Risk Factors For Women

Wednesday, August 4, 2010 by Stephen Sinatra
There are four key heart risk factors that affect women more than men. They include:

Diabetes. Diabetic women have a higher risk for heart disease than diabetic men. This is because the incidence of diabetes and its complications (including heart disease) is much higher in women. If you are a diabetic woman, your risk for heart disease is five to seven times normal, compared with a risk of only two to three times normal for a diabetic man. For you, proper heart sense means you should increase your physical activity and adhere to good cardiovascular nutrition to maintain a healthy body weight.

Overweight. Women have a higher heart disease risk from being overweight than men do. Studies indicate that being only 20 pounds overweight doubles a woman’s risk of heart disease. If you are overweight, I don’t want you to go on a diet. Instead, get physically active—it’s your most powerful weapon against fat—and eat more fresh fruits and vegetables, fish, and lean poultry.   That’s the “Dr. Sinatra” way to safe weight loss.

Cholesterol. Women have a higher risk for heart disease than men if they have low levels of HDL (“good”) cholesterol. For men, high levels of LDL present a greater risk, but for women, research indicates that a low HDL, not a high LDL, is the more significant risk factor for developing heart disease. The good news is that HDL is sensitive to factors such as smoking, obesity, and lack of exercise. So you can easily increase your HDL cholesterol by quitting smoking and dropping excess weight through a combination of healthy heart nutrition and physical activity.

High Triglycerides. When you get your cholesterol checked, also have your doctor check your level of triglycerides, which are another type of blood fat. A high triglyceride level (above 200 mg/dL) is more dangerous for women than for men, especially if you are a diabetic. Diabetic women with high triglycerides are up to 200 times more liekly to develop heart disease. A healthy triglycerides level can be obtained through exercise and weight control.

Though you should take the above risk factors very seriously, I want you to keep in mind that you can substantially reduce all of them. There are no secrets to doing this. Healthy eating, weight control, and regular physical activity are your weapons for keeping heart disease at bay.

For more information on heart risk factors or other cardiovascular problems for women, visit www.drsinatra.com.

The Truth About Cholesterol

Monday, August 2, 2010 by Stephen Sinatra
Contrary to popular belief, cholesterol is not a villain. Your body needs cholesterol to synthesize certain nutrients and hormones, construct the semi-permeable membranes around each of the 100 trillion cells that make up your body, and facilitate cell communication and memory in the brain.

Cholesterol moves through the body with the help of two proteins: LDL, or low-density lipoprotein, and HDL, or high-density lipoprotein. LDL carries ready-to-use cholesterol molecules that can be absorbed by cells that need it, and HDL picks up excess cholesterol and carries it back to the liver for recycling and excretion.

LDL, often referred to as the “bad cholesterol” only becomes unsafe when it interacts with molecular fragments called free radicals. The effect of such interaction is that the LDL becomes oxidized. Unlike normal LDL, oxidized LDL has toxic effects on the cells it attaches to. This is especially troublesome when oxidized LDL penetrates the endothelial cells lining the arteries because it contributes to—and accelerates—the inflammatory process.

When you get down to it, though, the real problem is not cholesterol—it’s whether your body’s antioxidant system can effectively neutralize the free radicals that damage LDL molecules.

In order to enjoy healthy cholesterol, it’s important to adhere to a cholesterol lowering diet, like my PAMM diet.  You’ll also want to exercise on a regular basis, which will also help to keep other cardiovascular problems away.

For more information on good cholesterol levels or reducing cholesterol, visit www.drsinatra.com.

Eight Stroke Prevention Tips

Monday, July 26, 2010 by Stephen Sinatra
The following eight tips can help you improve blood circulation and even reduce your risk of stroke:
  • Address any lifestyle-related or heart risk factors you have with your doctor.
  • Follow a good cardiovascular nutrition eating program, such as the PAMM diet.
  • Take 1–3 grams of fish oil daily.
  • For women over 65, take 100 mg of aspirin (equivalent to 1.25 baby aspirin) a day. (Beware of stomach bleeding, though, which is always a possibility with long-term aspirin use.)
  • Drink 1 to 3 cups of green tea and 2 ounces of pomegranate juice daily.
  • Take a 500–1,000 mg garlic supplement or eat one crushed clove daily. (Avoid this tip if you’re taking Coumadin.)
  • Be aware of your high inflammation marker scores: CRP, homocysteine, fibrinogen, and Lp(a).
  • Maintain good cholesterol levels, including an HDL less than 40.

Following these tips will minimizes your chances of having a stroke and will also help to keep other cardiovascular problems at bay. For more information on stroke, heart risk factors, cardiovascular problems and overall heart health, visit www.drsinatra.com.


Cardiovascular Concern: Drug Interactions

Friday, July 16, 2010 by Stephen Sinatra
Most people know there can be side effects from drugs, but they don’t realize that medications can interact with other medications, supplements, and even food. These interactions can drain vital nutrients from your body and counteract the healing powers of the drugs. As you deal with heart risk factors, including age, your nervous system becomes more sensitive, and you are more prone to developing side effects. The more medications you take, the more likely it is that adverse reactions will occur.

If you’re like many people dealing with cardiovascular problems, you may see a number of different specialists and holistic health practitioners. Please be sure to tell each one of them every drug you take.

This is mportant because they can unknowingly prescribe medications that interact adversely with something you’re already taking. Keep a list of all your drugs and supplements, and take it with you to every doctor’s appointment.

I write a lot about and prescribe CoQ10 to many of my patients. And I know that there are several drugs can interfere with CoQ10-dependent enzymes, lowering its concentration in the body. These include prescription drugs prescribed to help you maintain healthy cholesterol, as well as popular beta blockers.

Talking to your doctor and holistic health practitioner about your medications is vital to your ongoing good health.

For more information on cardiovascular problems, visit www.drsinatra.com. While there, sign up for FREE e-letters or subscribe to Dr. Sinatra’s monthly newsletter, Heart, Health & Nutrition.

When Does Cholesterol Become A Threat?

Friday, July 9, 2010 by Stephen Sinatra

Maintaining good cholesterol levels is important, but, contrary to popular belief, cholesterol is not a villain. Your body needs cholesterol to synthesize certain nutrients and hormones, construct the semi-permeable membranes around each of the 100 trillion cells that make up your body, and facilitate cell communication and memory in the brain.


Cholesterol moves through the body with the help of two proteins: LDL, or low-density lipoprotein, and HDL, or high-density lipoprotein. LDL carries ready-to-use cholesterol molecules that can be absorbed by cells that need it, and HDL picks up excess cholesterol and carries it back to the liver for recycling and excretion.


Healthy LDL cholesterol levels are always of great concern, as they should be, but few people know that it’s impossible for your cells to absorb too much of it. LDL becomes unsafe only when it interacts with molecular fragments called free radicals. The effect of such interaction is that the LDL becomes oxidized. Unlike normal LDL, oxidized LDL has toxic effects on the cells it attaches to.  

When you get down to it, though, the real problem is not cholesterol—it’s whether your body’s antioxidant system can effectively neutralize the free radicals that damage LDL molecules.

Here’s what you need to remember about cholesterol: It’s a relative heart risk factor and it’s influenced by other factors. You should also keep in mind that good cardiovascular nutrition and a cholesterol lowering diet can go a long way to helping you keep good cholesterol levels.

For more information on cholesterol guidelines, reducing hypertension, and overall heart health, visit www.drsinatra.com. While there, sign up for FREE e-letters or subscribe to Dr. Sinatra’s monthly newsletter, Heart, Health & Nutrition.

Lp(a) Cholesterol Guidelines

Thursday, July 8, 2010 by Jan Sinatra
Lp(a) cholesterol has been of great interest to many of you, and we’ve had many comments posted on the topic. I’d like to take the opportunity to answer a sound question from a concerned mom, because it is exemplary of what folks often ask us in the office that all of you can benefit from it.

Like many of you looking at the results of your cholesterol profiles, she reports that she is not sure what constitutes an alarming abnormal Lp(a) value. In her 50-year-old daughter’s case, the blood work read as follows:
  • Total Cholesterol:  173
  • HDL:   74
  • LDL:   87
  • LDL cholesterol-C:  90
  • Lp(a) : 12
In this particular case, there is no family history of cardiovascular disease, and the lipid panel results were within normal limits.

As with other blood level parameters, there may be some variation in normal ranges for Lp(a) as reported by different labs. I have seen some labs where up to 30 was within the normal range for the equipment and reagents they use. Our concerned mom reports that, for her daughter’s lab, anything over 10 is out of the normal range; hence her concern.

Her question is a good one. In the absence of any family history of cardiovascular problems and good cholesterol levels, how much should one be concerned about slightly elevated Lp(a)?

In this particular case, Dr. Sinatra and I would like to reassure her not worry about this finding. First of all, her daughter’s Lp(a) is only elevated two points (or  20 percent above the limit). Secondly, her high HDL “good” cholesterol levels of 74  (HDL > 60 for a woman,  and > 45 for men is considered desirable) is a very protective component. And, thirdly, there is no family or personal history of heart disease.
 
When do we get concerned? Dr. Sinatra takes action when he sees Lp(a) levels that are twice the normal limit (he sees some that are even four times higher or more!). In those cases, he recommends fish oil (a total of 2 grams/day in divided doses) and nattokinase (50 mg twice daily).

Even if your Lp(a) levels are normal, borderline, or even slightly elevated and you want to be more aggressive in your preventive medicine efforts, then just be sure that omega 3s are part of your daily vitamin and mineral plan. About one to two grams of a high quality fish oil—or squid oil—should do the trick.

Lp(a) may still be a new blood component to know about for many of you. Be sure to watch for an upcoming newsletter article on the seriousness of this risk factor. For other tips on healthy cholesterol levels, visit Dr. Sinatra's Web site. While there, don't forget to sign up for his FREE eLetters!

48 Hours After a Heart Attack

Wednesday, July 7, 2010 by Stephen Sinatra

Time is of the essence when you’re dealing with a heart attack. The best chance for survival and optimum recovery occurs if you are treated within two hours of the onset of symptoms.

At the hospital, things will move quickly. Up to 50 percent of the time, sudden death is the first symptom of heart disease, so any patient who survives the first two hours after a heart attack has passed a significant milestone. However, even with the best of medical care, 10–12 percent of those who survive the initial attack never leave the hospital (they die in the days following).


When it’s time for a patient to be discharged from the hospital, close caregivers should be present for any medical instructions because patients frequently don’t remember details. In fact, patients sometimes fail to recognize hospital staff members when they return for follow-up visits—that kind of psychological side effect is common during times of shock and trauma. At home, one of the biggest challenges that patients and loved ones face is a sense of day-to-day suspense. Many patients say they feel like they are just waiting for the other shoe to drop. These feelings are normal.


While I hope you’ll never need this information, I want you to be aware of it. I also want you to recognize common heart risk factors so that you can avoid ever being victim to heart attack or other cardiovascular problems. The key is prevention, which includes good cardiovascular nutrition, the ability to control high blood pressure, and maintaining healthy cholesterol and healthy triglycerides levels.

For more information on heart attack and stroke, heart risk factors, or other cardiovascular problems, visit www.drsinatra.com. While there, sign up for FREE e-letters or subscribe to Dr. Sinatra’s monthly newsletter, Heart, Health & Nutrition
 

Statin Drugs and Baby Aspirin

Monday, July 5, 2010 by Stephen Sinatra
When I am considering prescribing something to help a patient maintain healthy cholesterol or good blood pressure levels, I often select drugs that can treat plaque instability at the same time—like statins and baby aspirin.

And, as much as I strongly disagree with the use of statins for treating isolated high LDL cholesterol levels when heart disease is not apparent, I endorse statin therapy in situations where direct measures need to be taken to limit inflammation in anyone with documented coronary artery disease and to treat lipid disorders.

Researchers comment that we still lack the evidence to start pulling out the prescription pad and routinely ordering statins for anyone who has calcified heart valves. However, if you already have this condition, and are on a statin drug to treat your lipids, you should know that you may be improving your valvular function as well—or at least keeping it from worsening with age.

Statin drugs have been known to help stabilize plaque in acute coronary syndromes, so it’s logical to me that they have a probable impact on the calcification process and may also prevent plaque ruptures. In fact, research shows that patients who were admitted to a hospital on statin therapy, and had these medications discontinued while treatment focused on heart attack or unstable angina, actu­ally did not fare as well as those who continued to take their statins. Something about statins obviously assists in stabilizing unstable plaques.

Anyone taking a statin drug for an appropriate reason should be chasing it down with a minimum of 200 mg of standard CoQ10.

Low-dose aspirin—i.e., one baby aspirin a day or one half of a standard adult aspirin every other day—is known to help maintain good blood pressure levels and has also been shown to help prevent coronary events in patients with known coronary artery plaque. It will help reduce CRP levels, which lowers the risk of inflammation, result­ing in fewer cardiac events. I also recommend chewing on one adult aspirin while you wait for an ambulance if you think that you may be having a heart attack.

For more information on stain drugs, cholesterol levels, or other cardiovascular problems, visit www.drsinatra.com. While there, sign up for FREE e-letters or subscribe to Dr. Sinatra’s monthly newsletter, Heart, Health & Nutrition

The Magic of Garlic

Friday, July 2, 2010 by Stephen Sinatra
A few years ago, a small-scale trial conducted at UCLA explored the effects of aged garlic extract (AGE) on the natural course of calcified coronary artery (hard) plaque.  The 19 subjects who completed the protocol were well-matched for important variables like statin use and heart risk factors.

Researchers measured plaque at the study’s start and after twelve months. In the placebo group of ten people, the annual plaque progression rate was 22.2% (the range was actually an increase of 3.7 to 40.7% in this group).

Now, while levels for CRP and cholesterol parameters didn’t change significantly for any of the 19 individuals, the nine taking aged garlic extract tended to that it helped to increase HDL cholesterol levels and improved plasma homocysteine levels. Progression of cal­cific coronary disease detected by EBCT was significantly less, measured at 7.5% +/- 9.4%.

This preliminary finding should provoke larger scale investigation, but for now, it’s just another potentially good reason to add AGE to your program—especially if you know you have hard plaque and/or other cardiovascular problems.

For more information on cholesterol guidelines and cardiovascular problems, visit www.drsinatra.com.

The Cardiovascular Virtues of Green Tea

Monday, June 28, 2010 by Stephen Sinatra

In my newsletter, Heart, Health, and Nutrition, I’ve written a lot about inflammation as being a chief cause of cardiovascular problems, even more critical than the difficulty many Americans have with maintaining healthy cholesterol.

But, the good news is that a lot can be done to combat this potential killer. For example…

In a coronary arteriography study of nearly 400 Japanese men, those who loved their traditional green tea enough to drink at least a cup every day had a risk of heart attack significantly lower than men who were down­ing other beverages.

This study from the other side of the globe was extremely interesting. Researchers looked at green tea, black tea, cocoa, coffee, and red wine consumption and the heart. While investigators were hard-pressed to find any relationship between identifiable coronary artery disease and the dietary intake of any of these beverages, there was definitely a statistical association between green tea and heart attack; more of the former meant less of the latter.

The important property you get from a soothing cup of green tea is its natural COX-inhibiting effect, which translates to an anti-inflammatory effect.

Other natural COX-2 inhibitors that you can easily add to your diet include healthy spices like ginger, curcumin, oregano, onion, and garlic. These remarkable spices make for good overall cardiovascular nutrition.

For more information on good cardiovascular nutrition, visit www.drsinatra.com.

Prevent Lp(a) Cholesterol

Thursday, June 17, 2010 by Jan Sinatra
To offset the inflammation caused by elevated Lp(a) levels, Dr. Sinatra recommends that you try one or more of the following:
  1. Niacin:  Take up to a total daily dose of 1 gram (1 gram=1,000 mg) taken in one or two doses. Start at a dose of 125mg, then double it as tolerated, up to the full amount.
  2. Fish or squid oil: Take 2 grams daily of a good quality fish or squid oil (but not krill oil).
  3. Nattokinase: 50 mg daily.
  4. Bolouke: Boluoke contains the enzyme lumbrokinase, which has been shown to assist with the breakdown of fibrin, a protein involved in blood clotting. It is a Canadian product and can be purchased online. This is the only measure I know of that may actually lower your Lp(a). Take as directed.
  5. Delta tocotrienol: Take 100–200 mg of this natural form of vitamin E once a day.
  6. Get grounded! Remember, heart disease—like diabetes, cancer, and a host of autoimmune problems—is a disease caused by inflammation. In the case of heart disease, it’s the arterial walls that get inflamed. Once they puff up from inflammation and all kinds of debris that accumulate in the arterial walls, they then get clogged, especially if you have a tendency to clot. Grounding can help to reduce inflammation, and help avoid cardiovascular problems and prevent blood clots.
For more information on healthy cholesterol, visit www.drsinatra.com.


Cardiology Terminology: Lp(a)

Tuesday, June 15, 2010 by Jan Sinatra
Lately, Dr. Sinatra has been getting a lot of questions about the very small, dense, and highly inflammatory cholesterol particle known as lipoprotein(a)—or Lp(a) for short.

Good questions! Dr. Sinatra is one cardiologist who just doesn’t think that total cholesterol levels are the evil culprits behind cardiovascular problems that they have been made out to be. In fact, he believes that it is high time we switch the heart disease prevention paradigm from total cholesterol to Lp(a). There are too many folks with normal cholesterol levels having heart attacks not to believe that something is amiss.

But before we discuss ways to lower or prevent high Lp(a) levels, you must first know what you are up against.

Lp(a) is small, dense, highly inflammatory sub-fraction of a cholesterol particle and is made in the liver. Dr. Sinatra believes that it is so dangerous, it should be listed as a specific risk factor for heart disease—instead of total cholesterol.

While we know a lot about what it does in terms of how it affects the body, we are still in the theoretical stages in terms of how Lp(a) is metabolized and all of its physiological functions. So, here is what we’ve got on it to date:
  • Because of its small dense properties, Lp(a) has been shown to contribute to atherosclerosis;
  • Your Lp(a) level is often hereditary, with DNA determinants;
  • Lp(a) is thought to have something to do with coagulation and clot formation;
  • It can help with wound healing because of its ability to turn on inflammatory reactions; and
  • At high levels, it can promote excessive inflammation.
In short, Lp(a)’s  characteristics include:
  • small—it can easily sneak in and permeate the cell wall and wreak havoc;
  • dense— like a stone that sinks to the bottom, it can pile up on the walls of your blood vessels; and
  • highly inflammatory—it is a provocative little monster.
Everyone should know what their Lp(a) level is, especially anyone with known heart disease. Anyone with a family history of heart disease should also know, since Lp(a) blood levels are inheritable, and its production is controlled by a specific gene (an apolipoprotein(a) gene on chromosome 6q26-27 to be specific). That’s why we see elevated Lp(a) levels run in families. Also, if you are of African-American or some European heritages, you may be more at risk.

Lp(a) levels can range from 0.2 to 200, and because folks with very low Lp(a)s appear to be quite healthy, whatever its functions, they are not thought to be critical. Dr. Sinatra likes to see levels less than 35 nmol/l, according to the Quest Diagnostics standards he usually sees.

Here are the usual parameters, depending on how your lab expresses this level:

Desirable: < 14 mg/dL (< 35 nmol/l)
Borderline risk: 14 - 30 mg/dL (35 - 75 nmol/l)
High risk: 31 - 50 mg/dL (75 - 125 nmol/l)
Very high risk: > 50 mg/dL (> 125 nmol/l)           

Should you find your Lp(a) elevated, then you need take action. Later this week, I’ll tell you the most effective natural ways to reduce or even prevent Lp(a) cholesterol.

For more information on cholesterol guidelines and other cardiovascular problems, visit www.drsinatra.com.

Serum Ferritin (Iron) and Heart Disease

Friday, June 11, 2010 by Stephen Sinatra
Serum ferritin, better known as iron, is vital to human life because it stimulates the production of hemoglobin, the red blood cell pigment that carries oxygen to our cells. Without it, we couldn’t survive. However, research suggests that iron overload, or hemachromatosis, is a heart risk factor. Hemachromatosis is an acquired or heredi­tary defect of iron metabolism in which excess iron is deposited in tissues and not available for oxygen trans­port. Unless iron is lost through menstruation or donat­ing blood, over the years toxic levels can accumulate in your system.

In the early 1980s, Jerome Sullivan, a pathologist, noticed that women who had undergone hysterectomies had increased incidence of heart disease. He suggested that if losing blood protected menstruating women from heart disease, men donating blood might also have similar protection. Sullivan’s findings, published in Lancet in 1981, were years ahead of their time, yet his theories have been accepted only recently.

Women and Iron

Half of American women will die of cardiovascular problems, including heart attack and stroke, yet risk levels among women vary tremendously.

Menstruating women produce estrogen, which is heart protective, and most lose a significant amount of iron in the blood each month. This can add up to 400–500 mg of ferritin iron per year (about equal to two pints of blood).

In contrast, postmenopausal women are four times more likely to have heart attacks. Not only do they lose the protection of regular menstrual iron depletion, their levels of ferritin begin to rise steadily after menopause, more than doubling between 55 and 65, and even more after that.

If you are a postmenopausal woman, please be sure to have your doctor or holistic health practitioner check your iron level on a regular basis.  This is as important as maintaining healthy cholesterol, healthy triglycerides and health blood pressure when it comes to ensuring your wellness.

For more information on healthy heart nutrition for woman, visit www.drsinatra.com.

Sugar Equals Poor Cardiovascular Nutrition

Thursday, June 10, 2010 by Jan Sinatra
Just this year, Dr. Sinatra wrote in his newsletter Heart, Health & Nutrition about a study from the Journal of the American Medical Association showing that diets high in added sugars raise the levels of blood fats and increase cardiovascular disease risk. Specifically, people who ate about 20 percent of their daily calories in the form of sweeteners of any kind were much more likely to have lower HDL good cholesterol levels and higher triglyceride levels.

In the study, Emory University researchers surveyed about 6,000 adults and determined that average sugar intake was 16 percent of daily calories—21.4 teaspoons, about 359 calories. These findings also support guidelines released last year by the American Heart Association recommending that men keep their daily intake of added sugars below 150 calories (10 tsp.) and women limit themselves to 100 calories (6 tsp.).

I found the study perhaps most interesting for what it didn’t say: that sweeteners contribute to higher blood viscosity, a major overlooked component of cardiovascular problems. Research shows sugar stokes inflammation and increases C-reactive protein (CRP), and the added calories also contribute to weight gain and abdominal body fat, in turn, generating more CRP.

An earlier 2001 Harvard study found ultra-high CRP levels among women who ate large amounts of high-glycemic carbohydrates (ones that break down into glucose more quickly), such as potatoes, cereals, white bread, muffins, and white rice. Those women also tended to be overweight. So go easy on the sugar and limit your intake of foods that contain added sugar. Your body, especially your heart, will thank you.

For more information on healthy heart nutrition, visit www.drsinatra.com.

C-Reative Protein (CRP) and Your Heart

Wednesday, June 9, 2010 by Stephen Sinatra

C-reactive protein is a heart risk factor that the medical world has started to take note of. It’s a blood protein that, when found in elevated levels, may indicate a risk for heart attack and stroke.  

CRP can be detected when there is inflammation resulting from trauma or infection. Let’s look at some study results:  A 1985 Finnish study found that half of patients with coronary heart disease had high levels of an antibody known as C-reactive protein, compared with only 17 percent of healthy controls.

The Physicians Health Study indicated that C-reactive protein could predict future cardiovascular problems, such as heart attack in healthy and high-risk individu­als, and that high levels of this protein increase risk for heart attack and stroke.

In healthy postmenopausal women with levels of C-reactive protein and 11 other substances, the one-fourth with the highest C-reactive protein lev­els were 4.4 times more likely to have had a heart attack or other cardiovascular problem than the one-fourth with the lowest levels.

If you have cardiovascular problems or you’ve recently experienced a virus or urinary infection that could cause inflammation, have your doctor check your C-reactive protein levels. CRP can be detected when there is inflam­mation resulting from trauma or infection (including pneumonia, herpes, chlamydia, and possibly even a viral infection that simulates a cold). A simple blood test is as accurate as cholesterol and homocysteine screening in pre­dicting a person’s risk of heart attack and stroke.

For more information on heart risk factors and how to prevent them, visit www.drsinatra.com.

Prevent Blood Clots by Reducing Fibrogen

Monday, June 7, 2010 by Stephen Sinatra
Arteriosclerosis, or narrowing of the arteries, is the most common cause of heart disease, but in women younger than 45, we see more heart attacks caused by improper blood clotting that can be triggered by high fibrinogen levels.

Too much fibrinogen, an inflammatory product of blood coagu­lation, can make the blood clot too fast.

High fibrinogen levels aren’t the sole province of younger women. At age 57, one woman went to her doc­tor with signs of unstable angina. She had bypass and angioplasty, followed by drugs to help her maintain healthy cholesterol, as well as other conventional treatments.

Nine years later, she had a second heart attack and underwent a cardiac catheteriza­tion to reopen some of the grafts that had closed. In her mid-60s and depressed about the recurrence of her heart disease, she came to see me seeking alternative ways of minimizing her cardiovascular problems and healing her heart.

I prescribed a fish oil (EPA-DHA) supplement to pro­mote “slippery” blood platelets and help improve blood circulatin by neutralizing her fibrinogen and triglyceride levels. I also put her on my PAMM diet, my cardiovascular nutrition plan that includes much lower levels of carbohydrates (to combat her insulin resistance), plus healthy fats and garlic. I also recommended that she exer­cise to help her lose weight.

If these measures failed to support these critical blood parameters enough within three to six months, she agreed to go on natural estrogen therapy. Estrogen is important because fibrinogen levels rise with falling estrogen. Recent research suggests that estrogen replacement therapy can sig­nificantly reduce plasma fibrinogen levels.

The most important contributor to high fibrinogen levels is cigarette smoking: Smoking is just about the worst thing you can do for your health. According to research, almost half of all heart risk factors can be attributed to cigarette smoking.

While there may be some variations among labora­tories, an acceptable range for serum fibrinogen is less than 300 mg/dl; anything over 350 mg/dl is considered undesirable.

For more information on heart risk factors and how to prevent them, visit www.drsinatra.com.