Statin Drugs and Natural Solutions for Healthy Cholesterol

Friday, March 5, 2010 by Stephen Sinatra

Some of the most commonly prescribed drugs for maintaining good cholesterol levels are statins like Zocor (simvastatin), Lipitor (avorastatin), Mevacor (lovastatin), Pravachol (pravastatin), and Lescol (fluvastatin).

These drugs can be dangerous if taken with high levels of long-acting niacin (vitamin B3). Side effects also include dizziness, headache, extreme fatigue, swelling of the ankles, muscle weakness, and liver toxicity.

In both men and women, statins may weaken the heart muscle because they lower CoQ10 levels. In women especially, statin drugs may deplete levels of CoQ10, contributing to a weakened immune system.

Still, if you have moderate to severe heart disease involving multiple vessels, I recommend statin drugs to help you obtain and maintain healthy cholesterol levels. In addition, I recommend the following natural solutions:

  • Make sure you take a minimum of 150 mg of standard CoQ10 per day, or 50–60 mg of the hydrosoluble form, to offset the drug’s depleting effect.
  • Niacin is one of my favorite cholesterol-lowering agents if you are not on a statin drug, because of its ability to increase HDL cholesterol (the “good” cholesterol) and lower LDL cholesterol levels (the “bad” cholesterol). Low doses in the range of 100–300 mg three times daily are often effective without resulting in side effects of flushing, heartburn or gout attacks. A prescription form called Niaspan (750–1,500 mg) appears to be well-
    tolerated by most people with minimal side effects.
  • Tocotrienols are antioxidants in the vitamin E family. Research suggests that they act much like statin drugs, minus the adverse side effects, by interfering with the liver’s ability to produce cholesterol. As little as 50 mg per day can have a positive effect.
  • My Pan-Asian Modified Mediterranean-type diet (PAMM) is great for this and for overall cardiovascular nutrition. It’s rich in fiber, healthy fats (omega-3s from fish and fish oil), garlic and onions (two potent cholesterol-busters), and fresh fruits and vegetables. Fiber helps soak up cholesterol and cleanse the colon, preventing rapid absorption of cholesterol.
  • Flaxseed is high in alpha linolenic acid and fiber, vital for healthy heart function.
  • Soy helps prevent the oxidization of LDL and subsequent buildup of artery-clogging plaque. Soy also can help with reducing cholesterol levels, help ease menopausal symptoms, and may help protect against cancers of the breast and prostate.
  • L-arginine—2–4 grams three times a day. TwinLab and Great Earth make good supplements that are widely available in health food stores.

Reducing Cholesterol With Statin Drugs?

Wednesday, March 3, 2010 by Stephen Sinatra

HMG-CoA reductase inhibitors, more commonly known as statins, are among the most aggressively marketed drugs for producing good cholesterol levels. In clinical studies, statins achieved a striking reduction in cardiovascular problems such as heart attack, bypass, and hospitalization.

Statins are potent anti-inflammatory drugs that have been shown to be able to do a good job of reducing cholesterol levels, while also decreasing the number of deaths from heart attack and stroke. However, they do come with a host of side effects, including a slight increased risk of breast cancer for women taking statin drugs. Because of the studies, I prefer to err on the side of caution when it comes to their use.

In my next blog post, I’ll share safe, natural solutions that can help you maintain healthy cholesterol levels.

Statin Drugs Will Not Reduce Lp(a)

Wednesday, February 24, 2010 by Stephen Sinatra

Drugs typically prescribed for reducing cholesterol have no impact on Lp(a) levels. In fact, a study involving these drugs showed an increase in Lp(a) levels! And therein lies the dilemma.

While drugs prescribed to help you attain and maintain healthy cholesterol can reduce LDL, they can’t alter Lp(a). If you find that Lp(a) runs in your family, you must attack it with an alternative approach. Here’s what I recommend:

  • Follow my Pan-Asian Modified Mediterranean diet, making sure to eat fresh fish at least two to three times a week. Eat fresh fruits, legumes, cold-water fish such as salmon, sardines, and mackerel or fish oils, particularly docosahexaenoic acid (DHA), which blocks the inflammatory and blood-clotting capabilities of Lp(a). Omit saturated fats. Instead, choose monounsaturated fats like olive oil and polyunsaturated fats like alpha-linolenic acid, found in flaxseed and flaxseed oil.   (These are excellent tips to adhere to for overall cardiovascular nutrition.)
  • Take 100 mg of niacin, twice a day. If you experience side effects like flushing, headache, and diarrhea, follow the diet and stop the niacin. You can try a lower dosage at a later date, then slowly increase the dose to 500 mg a day, twice a day for further protection. TwinLabs' quick-acting Niacin is a good product.
  • Take 1–2 grams of vitamin C and 100–200 mg of CoQ10 each day.
  • Policosanol—20 mg daily at bedtime.
  • Exercise regularly.
  • Ask your doctor about screening techniques to assess your heart risk factors. If you’re concerned, you and your family members should have your Lp(a) and other risk factors (homocysteine, fibrinogen and serum ferritin) evaluated by your doctor.
  • Be aware of other risk factors for cardiovascular problems, including smoking, high blood pressure, obesity, glucose intolerance and repressed emotions, which can have a harmful effect on the health of your heart.

Statin Drugs Will Not Reduce Lp(a)

Friday, February 19, 2010 by Stephen Sinatra

 Drugs typically prescribed for reducing cholesterol have no impact on Lp(a) levels. In fact, a study involving these drugs showed an increase in Lp(a) levels! And therein lies the dilemma.

While drugs prescribed to help you attain and maintain healthy cholesterol can reduce LDL, they can’t alter Lp(a). If you find that Lp(a) runs in your family, you must attack it with an alternative approach. Here’s what I recommend:

  • Follow my Pan-Asian Modified Mediterranean diet, making sure to eat fresh fish at least two to three times a week. Eat fresh fruits, legumes, cold-water fish such as salmon, sardines, and mackerel or fish oils, particularly docosahexaenoic acid (DHA), which blocks the inflammatory and blood-clotting capabilities of Lp(a). Omit saturated fats. Instead, choose monounsaturated fats like olive oil and polyunsaturated fats like alpha-linolenic acid, found in flaxseed and flaxseed oil.
  • Take 100 mg of niacin, twice a day. If you experience side effects like flushing, headache, and diarrhea, follow the diet and stop the niacin. You can try a lower dosage at a later date, then slowly increase the dose to 500 mg a day, twice a day for further protection. TwinLabs' quick-acting Niacin is a good product.
  • Take 1–2 grams of vitamin C and 100–200 mg of CoQ10 each day.
  • Policosanol—20 mg daily at bedtime.
  • Exercise regularly.
  • Ask your doctor about screening techniques to assess your risk factors for heart disease. If you’re concerned, you and your family members should have your Lp(a) and other heart risk factors (homocysteine, fibrinogen and serum ferritin) evaluated by your doctor.

Heart Risk Factors for Women Versus Men

Sunday, February 7, 2010 by Stephen Sinatra
Let’s take a look at how women’s risk factors for heart disease are different from men’s.


Diabetes.
Diabetic women have a higher risk for heart disease than diabetic men. This is because the incidence of diabetes and its complications (including heart disease) is much higher in women. If you are a diabetic woman, your risk for heart disease is five to seven times normal, compared with a risk of only two to three times normal for a diabetic man. For you, proper heart sense means you should increase your physical activity and watch your diet to maintain a healthy body weight.


Overweight.
Women have a higher heart disease risk from being overweight than men do. Recent studies indicate that being only 20 pounds overweight doubles your risk of heart disease. If you are overweight, I don’t want you to go on a diet. Instead, get physically active—it’s your most powerful weapon against fat—and begin eating more fresh fruits and vegetables, pasta, fish and lean poultry.  Eating this way is what I call “healthy heart nutrition” and it just makes sense. (See other blog entries for additional advice on cardiovascular nutrition.)


Cholesterol.
Women have a higher risk for heart disease than men if they don’t have good cholesterol levels. More specifically, if they have have low levels of HDL (“good” cholesterol) they increase their heart risk factors.


You probably already know that there are two types of cholesterol. LDL is the “bad” cholesterol, which oxidizes in your blood and forms the plaque that clogs arteries. HDL carries LDL out of your blood vessels before it can do its damage. Volumes of data have shown that a high LDL is a powerful risk factor for heart disease in men. But for women, the story is different. Recent research indicates that a low HDL, not a high LDL, is the more significant risk factor for a woman to develop heart disease. (This means that some women may need to increase HDL cholesterol levels.)


The good news is that HDL is sensitive to factors such as smoking, obesity and lack of exercise. If your HDL is low (less than 35 mg/dL) you can raise it by quitting smoking and dropping excess weight through a combination of smart eating, healthy heart nutrition, and physical activity such as walking and dancing. If you are postmenopausal, you might also consider estrogen replacement therapy (ERT), which raises HDL, lowers LDL, and has other beneficial effects on your heart. Have your HDL level checked six weeks after you start an HDL-raising program. Chances are you will see a change for the better.


High Triglycerides.
When you get your cholesterol checked, I also want you to have your doctor check to see if you have healthy triglycerides levels. Triglycerides are another type of blood fat. A high triglyceride level is more dangerous for women than for men, so if your triglycerides are elevated (above 200 mg/dL), I want you to put some effort into lowering them, especially if you are a diabetic. This is because if you are a diabetic woman who also has high triglycerides, your risk of developing heart disease increases to 200 times normal. Please stop and think about this. You can lower your triglycerides using the powerful combination of exercise and weight control.

Low-Carb Diets Can Make It Difficult To Achieve Healthy Cholesterol

Monday, February 1, 2010 by Stephen Sinatra

Many of today’s fad diets revolve around modifying insulin resistance by consuming low-carbohydrate, high-protein foods and also advocate eating foods high in saturated fats and dairy products. This type of diet is likely to contain high levels of insecticides, pesticides, and radiation, which in the long run may increase your risk of cancer of the bowel, prostate, and breast and can increase your heart risk factors.


Also, as you start to lose weight and your body is forced to break down stored fat for energy, your good cholesterol levels may be challenged and it may become difficult to keep them within the recognized cholesterol guidelines. This may be an artificial rise in cholesterol, however, it is a good idea to be cautious and work with a physician if you decide to start one of these diets.


Based on this, I suggest that anyone trying to lose weight adhere to a diet akin to my Pan-Asian Modified Mediterranean diet, making sure to eat fresh fish at least two to three times a week. You’d can also enjoy fresh fruits, legumes, cold-water fish such as salmon, sardines, and mackerel or fish oils, particularly docosahexaenoic acid (DHA), which blocks the inflammatory and blood-clotting capabilities of Lp(a).

I’d also urge you to omit saturated fats. Instead, choose monounsaturated fats like olive oil and polyunsaturated fats like alpha-linolenic acid, found in flaxseed.

Healthy Heart Nutrition Plan

Friday, January 22, 2010 by Dr. Sinatra’s Team
We have received several comments expressing a concern on proper supplementation—which nutrients are important, the right dosage, getting the biggest bang for your buck, etc. When we developed a nutrient line with Dr. Sinatra, we asked ourselves the very same questions.

We (and Dr. Sinatra!) believe that the foundation for healthy heart nutrition lies first and foremost in a solid multinutrient. A good multivitamin and mineral formula should contain, among other nutrients, significant levels of antioxidants, calcium, vitamin D, magnesium, and folic acid.

And no cardiovascular nutrition advice would be complete without discussing fish oil. The omega-3s found in a high-quality fish oil are crucial for cardiovascular nutrition, promoting healthy blood pressure levels, good triglycerides, HDL/LDL cholesterol ratios, and more.

Lastly, given the time of year, you may also want to take nutrients that provide solid immune protection. A good immune product should contain a blend a nutrients, including quercetin, alpha lipoic acid, resveratrol, astaxanthin, and bromelain. Not only do many of these nutrients have heart benefits, but they also help to strengthen your immune system, as well as promote healthy aging.

Healthy Heart Nutrition Starts with Flax

Wednesday, January 13, 2010 by Jan Sinatra

Pure flax oil is the world's most abundant source of omega-3 fatty acids, containing an amazing 55 percent by weight. As such, flax oil offers incredible health benefits that should not be discounted.

Specifically, flax contains alpha linolenic acid, which your liver must break down to form the more commonly known omega-3 fatty acids EPA and DHA. There has been debate about whether alpha linolenic acid effectively converts to EPA and DHA. However, research shows that it does.

Research suggests that increased consumption of omega-3 fatty acids can reduce several cardiovascular problems by helping to promote healthy cholesterol levels, as well as healthy triglycerides. They also help keep blood pressure levels in the normal range. In addition, omega-3s help reduce circulatory problems by supporting healthy circulation and blood flow throughout the body.

One of the best ways to reap these benefits from flax by eating ground flaxseed. And yes, you must grind the seeds to release the oil. Otherwise, they'll pass right through you, undigested. I recommend getting a coffee grinder and dedicating it to flaxseed, because you don't want to mix ground coffee and flax. It's not a taste sensation! Also, you must use the flax within hours of grinding it. Once exposed to air, the oil in ground flax goes rancid quickly. (For the same reason, flax oil must be refrigerated.)

You can sprinkle ground flax on just about anything—soups, stews, ice cream, you name it. Above all, avoid cooking with ground flax, because again, the oil will become rancid.

The beauty of flaxseed is that you get significant amounts of protein and fiber in a tiny package. In a typical 2 oz. serving (1/4 cup), you'll get approximately 11 grams of fiber and 10 grams of protein. Exact amounts will vary with the quality of the flaxseed and how it's grown.

Easy Flax Shake

One of the easiest (and tastiest!) ways to get your daily flax is to add it to a shake or smoothie. Here’s one of my favorite versions.

1.    Grind up 2 tablespoons of organic flaxseed.
2.    In a blender, add 8 to 10 ounces of chilled soy milk, ½ a banana, 1 cup of your favorite berries, and the freshly ground flaxseed.
3.    Blend well and enjoy!

Viva Las Vegas: The Annual Anti-aging Conference

Tuesday, January 5, 2010 by Jan Sinatra
On the Road with Dr. Sinatra - December 2009

Every December, Dr. Sinatra and I always head to the American Academy for Anti-Aging Medicine's annual conference in Las Vegas. (There is great video of Dr. Sinatra presenting at the 14th annual Anti-Aging Medicine conference in 2008... check it out!)

This engaging conference is abundant with many stimulating and educational sessions on the latest topics and technologies in the world of alternative medicine. While I personally have some resistance to the term “anti”-aging, the caliber of speakers and vendors there is downright exceptional!

I can remember over a decade ago, Drs. Ron Klatz and Stephen Goldman had the vision to create this collegial academy so that there was a format for formal training in areas of alternative medicine for doctors and other healthcare professionals who are motivated to practice integrative medicine. Their first conference was held at the cozy and charming Alexis Park Hotel on Harmon Boulevard in Las Vegas. Now, the American Academy for Anti-Aging Medicine has several annual conferences in the US and the UK, and attendance in Vegas is so great that, for years, they been held in the larger hotels like the Venetian and Mandalay Bay.

Dr. Sinatra has been board certified in anti-aging medicine for years. He also contributes questions to their certification exam, has given some of the oral exams, and has lectured on various cardiology topics at the American Academy for Anti-Aging Medicine for over a decade. This year, he taught a six-hour fellowship program on the subject of the metabolic cardiology treatment approaches that he has been using successfully for years. The talk included approaches for lowering blood pressure naturally, as well as how to increase HDL cholesterol levels, lower LDL cholesterol levels, and improve blood circulation without drugs.

Dr. Sinatra spoke at the last two annual Orlando-based American Academy for Anti-Aging Medicine conferences held in April. There he met Houston-based attorney Richard Jaffee. After hearing him lecture on energy medicine and the emotional aspects of disease, Mr. Jaffee introduced Dr. Sinatra to his friend Suzanne Somers. The end result: Suzanne interviewed Dr. Sinatra for her book Knockout, which was released in October 2009. Like Rick Jaffee, Dr. Sinatra was honored to help with her mission to inform the public about alternative cancer care options that are available.

Who knows what may happen in 2010? For now, a plan to continue to teach other physicians at the Boca Raton American Academy for Anti-Aging Medicine training module in March.

Your Cholesterol Lowering Diet Should Include Flaxseed

Thursday, December 31, 2009 by Stephen Sinatra

Cholesterool Lowering Diet and Flax SeedCrushed flaxseed is a perfect food for a cholesterol-lowering diet. It contains essential fatty acids, high-quality protein, vitamins, precious phytonutrients, and lignans, as well as soluble fiber and insoluble fiber, all of which promote healthy cholesterol. In fact, research on soluble fiber shows that total cholesterol can be reduced by 11 percent and LDL cholesterol by 18 percent over a two- to three-week period.

For now, I hope all of you—even those of you whose cholesterol levels are in the normal range—will drink one flax shake a day. Many of my patients have lowered their cholesterol and lost weight when I 've put them on a flax shake. Give it a try!

 

Walking Can Prevent Heart Attack and Stroke

Thursday, November 5, 2009 by Stephen Sinatra

I can’t say enough about the health benefits of exercise. It strengthens the heart and circulatory system, builds stamina, and improves mood. It’s also an effective means for lowering blood pressure levels, increasing HDL cholesterol, and improving poor blood circulation.

I’m often asked what the best form of exercise is. I say it’s the one you will consistently do! Walking, dancing, cycling, lifting weights—it doesn’t matter. The goal of exercise is simply to get out and get moving.

That said, I have to admit I’m a big fan of walking. It’s simple, doesn’t require special equipment or a gym membership, and it can help reduce your risk of heart attack and stroke. In a study reported in the Journal of the American Medical Association (JAMA), 4,065 nurses ages 40 to 65, without cardiovascular disease or cancer, completed detailed physical activity questionnaires. The surveys revealed that walking was associated with reduced risk of stroke.

Walking is easy to incorporate in your day. Walk up and down stairs instead of taking elevators. Steadily increase the distance while walking your dog. Instead of parking in the closest space to the store or office entrance, park at the far end of the parking lot. Consider walking short distances for errands instead of driving.

If you’ve been inactive for a while, start slow. Walk 10 minutes every other day for one week. Each week, increase your time by increments of 5 or 10 minutes. Within a month, you’ll be taking 30-minute strolls. Do this every other day, and you’ll have a good workout routine. Five days a week is optimal.

As for speed, you don’t have to maintain a brisk pace. Actual walking speed isn’t as important as we’ve been led to believe. In fact, researchers in the JAMA study I mentioned found that speed didn’t matter; it was the length of time women walked that was significant.

Simple, right? If you agree, lace up those sneakers and get out there. It’s one of the simplest—and most effective—steps you can take (literally) to prevent heart attack, stroke, and other cardiovascular problems.

 

Bring Down High Triglyceride Levels

Thursday, October 29, 2009 by Stephen Sinatra

With all of the unnecessary attention lavished on HDL and LDL cholesterol levels, the importance of healthy triglycerides has been largely lost. And that’s too bad—because keeping them in a healthy range is essential to heart health.

Triglycerides are the chemical form of most fats in the body. The triglycerides in your blood come from dietary sources, primarily fats and carbohydrates. I consider a healthy triglyceride level to be 50–150 mg/dL. Levels above that have been linked to coronary artery disease and metabolic syndrome.

Given that the typical American diet is laden with processed and fast foods, it’s no surprise that high triglyceride levels are a problem for many people. To bring them down, cut back on the amount of sugar and carbohydrates in your diet, and eat more protein. I would also strongly recommend that you exercise regularly. Lifestyle changes such as these are very effective in keeping triglycerides in the healthy zone. Remember, the lower your weight, the lower your triglycerides, so weight loss and weight management are KEY to success!

Another good option for lowering triglycerides is a high-quality fish oil supplement. Start with 2–3 grams daily in divided doses, and let me know how it works for you.

 

Soy Foods for Healthy Cholesterol

Wednesday, August 26, 2009 by Kimberly Day

It’s one thing to say “eat more soy” to help maintain good cholesterol levels or as part of a plan for reducing cholesterol. It’s quite another to actually put that advice into action. So here are my top recommendations of soy-based foods and how to use them.

Soy is known to be one of the two most genetically modified foods in the United States (corn is the other). Given this, I strongly recommend sticking with “true” soy foods, meaning edamame (the beans themselves), tofu, and tempeh (fermented soy). And always, always choose organic.

Easy Edamame

Edamame is the easiest of the three to work with! For a delicious finger food (and great alternative to greasy, unhealthy chips), steam edamame, toss with sea salt, and enjoy!

I also like to toss edamame into my salads for a quick hit of protein. In fact, 1/2 cup of edamame gives you 150 mg soy isoflavones a day.

Turn Up Your Tofu

Let’s face it, tofu is rather bland. But that doesn’t have to be the case! Tofu is like a culinary chameleon, meaning that whatever you add to tofu, it magically “becomes.” Therefore, the secret to tofu is marinade and spice.

The easiest tofu recipe I know is to mix 2/3 cup tamari sauce, 2/3 cup olive oil, and 1/3 cup balsamic vinegar. Add 2-3 tablespoons of your favorite spice mix and blend well. Cut tofu block into five slices. Add to marinade and refrigerate (covered) for at least four hours. Lightly sauté and you have a delicious meal that can be pair with virtually any side dish!

You can also “soak” tofu in your favorite barbeque sauce, cut into slices, and grill. So delicious! Pair with a salad and some roasted vegetables and you have an easy, delicious, healthy meal in no time. And, just one cup of tofu provides 70 mg soy isoflavones as part of a healthy cholesterol loweing diet.

Tempting Tempeh

This one seems to baffle even the most devout soy lover. The simplest answer? Treat like ground meat. Simply crumble tempeh and lightly sauté with onions and peppers. Add some diced tomatoes and your favorite blend of Italian spices and you have a delicious pasta sauce!

Another favorite? Add tempeh to chili to give it a protein-powered boost without altering the flavor of your favorite recipe. Again, crumble the tempeh to achieve the best texture and mouth feel. And, like tofu, just one cup of tempeh gives you 70 mg soy isoflavones.

If you have any recipes, tips, or questions regarding healthy heart nutrition, please send them in so we can share them with other healthy epicures!

Soy Promotes Healthy Cholesterol Levels

Thursday, August 20, 2009 by Kimberly Day

More than 30 clinical studies have shown that soy is highly effective as part of a cholesterol-lowering diet. Case in point, an August 1995 meta-analysis from the New England Journal of Medicine found that people who ate an average of 47 grams of soy protein per day had a 13 percent decrease in LDL cholesterol levels, a 10.5 percent decrease in triglycerides, and a nine percent decrease in total cholesterol levels.

A November 2001 issue of Archives of Internal Medicine also found that a high consumption of legumes, including soybeans, meant a lowered risk of coronary heart disease (CHD). They concluded that increased legume intake may be an important part of a dietary approach to preventing CHD.

Additionally, a report in the August 2002 issue of Arteriosclerosis, Thrombosis and Vascular Biology found that a diet rich in tofu and other soy products may help protect postmenopausal women from arterial disease. According to researchers, phytoestrogens were associated with less arterial stiffness among more than 400 postmenopausal women. The benefit was most pronounced among the oldest women, or those who had been postmenopausal the longest.

Surprisingly, even the FDA agrees that soy is beneficial for maintaining good cholesterol levels. In 1999, they authorized of the use of health claims on the labeling of foods containing soy protein, based on research which shows that soy foods may reduce risk of coronary heart disease by lowering blood cholesterol levels. According to the FDA, foods must contain 6.25 grams per serving of soy protein in order to qualify for the claim, and a daily intake of 25 grams is recommended in order to achieve a significant cholesterol-lowering effect. Now that's healthy heart nutrition!

Improper Grilling Can Mimic Cardiovascular Problems

Wednesday, August 12, 2009 by Kimberly Day

Now that the summer is in full force, you are likely hooking up the barbeque and gathering with friends to enjoy dinner in the great outdoors. As enjoyable as these get-togethers can be, research has shown that grilling meat at high temperatures can create a number of harmful compounds.

 

High heat from an open flame creates COPs, highly carcinogenic compounds that are similar to the oxidized cholesterol found in your bloodstream. Along with the COPs, high heat creates other groups of harmful compounds, including heterocyclic amines (HCAs), compounds that have been found to increase your risk of several of the most common kinds of cancer, including breast, prostate, colon, and stomach cancers.

 

Tasty Ways to Protect Your BBQ

 

Fortunately, a marinade consisting of 10 percent plain soy sauce and one percent sugar has been found to cut the production of COPs by more than 60 percent. Plus, additional research also shows that adding tart cherries, red grapes, or plums (all good sources of pigmented antioxidants) to hamburger meat can cut HCA formation by 94 percent.

 

While it’s easy enough to mix some soy sauce or a handful of crushed cherries or grapes into a pound of lean hamburger or ground turkey, I prefer to use a marinade for my favorite fish. Not only do you get delicious protection from the potentially harmful side effects of grilling, but you get the heart-health benefits of omega-3s, including increased HDL cholesterol and LDL cholesterol levels, improved blood circulation, and reduced risk for heart attack and stroke.

So eat up and enjoy how delicious healthy heart nutrition can taste!

 

A Taste of the Orient

 

This taste delight combines the protection of soy sauce with the essential fatty acid and fiber benefits of nuts. I find this marinade works best with a mild fish such as halibut.

 

1/2 cup organic almond butter

1/3 cup soy sauce

2 tablespoons lime juice

1 tablespoon raw honey

1/2 teaspoon powdered ginger

1/8 teaspoon cayenne pepper

  1. Warm almond butter in small saucepan over medium low heat.
  2. When slightly softened, add soy sauce and remaining ingredients and blend well.
  3. Remove from heat and pour into large, shallow bowl.
  4. Add your fish and marinate in refrigerator for one to three hours.
  5. Can also be used as a sauce.
     

 

Does Healthy Cholesterol Really Lower Risk of Dementia?

Friday, August 7, 2009 by Stephen Sinatra

Earlier this week, a new study by Kaiser Permanente reported an association between high cholesterol levels and increased risk of Alzheimer’s disease or dementia. Researchers followed close to 10,000 people for 40 years and found that people who had high or borderline high cholesterol levels at ages 40–45 had much greater chances of significant mental decline later in life. Risk was 66 percent higher for people with high cholesterol (>240 mg/dL), and 25 percent higher for people with borderline high levels (200–239 mg/dL).

Alzheimer’s is a frightening condition, and these results are provocative. I have no doubt whatsoever that somewhere there’s someone saying, “This is another reason why we need to keep reducing cholesterol.”

But when it comes right down to it, these results merely show that people with high cholesterol tended to have a higher incidence of dementia. They don’t prove that reducing cholesterol will prevent future illness.

If there’s one point I want you to take away from this study, it’s this: Cholesterol is no more than a biological marker that can reveal what’s going on in the body. When it’s high, it usually means there’s usually an underlying problem somewhere—and in this case, those problems also may have had an effect on brain health.

For example, the study provided no information about the general health of the participants, so it’s impossible to know if they had health conditions—such as diabetes, metabolic syndrome, or being overweight—that would predispose them to inflammation and higher LDL cholesterol levels. (Inflammation has also been linked to Alzheimer’s, and more closely.) We also don’t know about their lifestyle habits. Did they eat diets high in carbohydrates, sugar, or trans fats? These, too, stoke inflammation, and trans fats, specifically, have been shown to destroy brain cells.

If you have high cholesterol, rest assured that you’re not destined for Alzheimer’s. However, I would encourage you to address the risk factors that are causing your LDL cholesterol levels to rise above the optimum level. Avoid excess sugar by following an   organic Mediterranean-style diet rich in fish, DHA-fortified eggs, whole grains, fruits, and vegetables; keep your blood pressure in check by better managing stress; and lose weight by exercising every day. If you are a man, keep your waistline to less than 40 inches, and if you are a woman, to less than 36 inches (this helps prevent metabolic syndrome). When these fundamental issues are taken care of, not only will your cholesterol level fall, but you will reduce your risk for all age-related disease.

 

Two Birds, One Stone: Niacin Increases HDL and Lowers Lp(a)

Tuesday, July 28, 2009 by Stephen Sinatra

You’ve heard me say time and again that reducing cholesterol is not the magic bullet that will prevent heart attack and stroke. I stand by this statement wholeheartedly—but I don’t want you to interpret it to mean that cholesterol is unimportant.

Optimum cardiovascular health requires maintaining a healthy cholesterol ratio—that is, keeping your LDL cholesterol levels (the so-called “bad” cholesterol) in proper balance with your HDL levels (the “good” type of cholesterol). It also calls for minimizing the amount of Lp(a) in your blood, and not letting your triglyceride levels get out of hand.

Although regular exercise and a cholesterol lowering diet will go a long way toward helping you achieve these goals, I also recommend that you try some targeted nutritional supplements for an extra boost. One of them is niacin (vitamin B3). It’s a fantastic nutrient that can help you increase HDL cholesterol, as well as lower both triglycerides and the dangerous subtype of cholesterol known as Lp(a).

These are huge benefits. For me, keeping HDL levels high and Lp(a) down are more significant than lowering LDL or even total cholesterol. Elevated Lp(a) is a serious, widespread, and underemphasized problem, and niacin is probably one of the best nutrients to lower it. And the higher your good cholesterol levels, the more protection you have in your blood vessels.

The only downside to niacin is the flushing sensation it generates. This hot, tingly, pins-and-needles feeling is disconcerting to a lot of people, but it usually lasts no more than 30–60 minutes, and it is most pronounced during the first week or so that you take the supplement (it can also occur when you increase your dosage). You can find no-flush forms of niacin, but they’re not as effective. I would stick with the regular kind.

I recommend taking 1–2 g a day in divided doses with meals. Start with 250 mg and slowly work your way up to minimize the flushing effect. Let me know how it works for you!

 

10 Must-Know Facts About Cholesterol

Monday, June 1, 2009 by Stephen Sinatra

One of the most important parts of maintaining healthy cholesterol is understanding how your body uses and manages this essential lipid. Why? Because having a cholesterol level that is too low is just as dangerous as having a cholesterol level that is too high. Most people don't realize it, but blindly following the cholesterol guidelines put forth by pharmaceutical companies (whose primary interest is to sell you their drugs, not to make you healthy) could put your long-term health in jeopardy.

To help you get some perspective on what constitutes a good cholesterol level, I've identified 10 vital facts about cholesterol in the body. Keep them in mind the next time your doctor raises the issue of reducing cholesterol, and make sure that any decision to do so is truly in your best interest (and if you must improve your numbers, opt for natural therapies such as a cholesterol lowering diet, as well as lifestyle changes and nutritional supplements that can help increase HDL cholesterol and reduce LDL cholesterol levels).

1) Cholesterol is a raw material made by your liver, brain, and almost every cell in your body. Enzymes convert it into vitamin D, steroid hormones (including the sex hormones estrogen, progesterone, and testosterone, and stress hormones), and bile salts needed for digesting and absorbing fats. Cholesterol is a major part of the membranes surrounding cells and the structures within them.

2) The body makes cholesterol as needed. When you eat more in your diet, the body makes less. If you eat less, the body makes more. On average, 85 percent of blood cholesterol is made in the body, and the rest comes from food.

3) You can have different levels of cholesterol at different times of the day.

4) Cholesterol tends to go up in the winter and down in the summer.

5) Cholesterol soars after any surgery, and it increases when you have an infection, mental stress, or have suffered a heart attack. The reason for this is that cholesterol is a healing agent needed to help create new cells, and it’s produced whenever healing is required. Your cholesterol level will also rise and fall depending on exposure to environmental agents and toxins.
 
6) When a doctor finds a high level of cholesterol, instead of reaching for the prescription pad, he or she should look for the reason the cholesterol is high and treat the cause. If the cause is successfully addressed, cholesterol often comes down.
 
7) It’s interesting to note that the herbs, antioxidants, and nutraceuticals that reduce cholesterol do so by neutralizing damaging agents in the blood stream. Thus, the liver doesn’t have to produce as much cholesterol. Moreover, the supplements support other biochemical processes necessary to heal wounds.
 
8) The endothelium is the razor-thin lining of blood vessels. The damaging agents we are exposed to—toxic chemicals, pathogens, free radicals, and inflammatory substances—wind up in our blood stream and damage this thin layer of cells. When this happens, the liver sends LDL to the site to make repairs. As the healing process concludes, the spent LDL particles are carried back to the liver by HDL and removed from the body.
 
9) The brain is particularly rich in cholesterol and accounts for about one-quarter of all the cholesterol we have. About 20 percent of the fatty myelin sheath that coats every nerve cell and fiber is made of cholesterol, and neuron function depends on it. It’s not surprising that a connection has been found between naturally occurring cholesterol and mental function, and that lower cholesterol levels are linked to poorer cognitive performance.
 
10) Some research suggests that doctors should be extremely cautious about prescribing statin drugs to the elderly, particularly those who are frail. I agree. I have seen frail individuals become even weaker and more prone to infections after taking these medications. Many of these patients later told me that their strength, energy, appetite, and vitality returned when they discontinued the statins. These folks clearly need their cholesterol—as do the very young.

Everyday Foods Can Reduce Cholesterol

Thursday, March 19, 2009 by Stephen Sinatra
You know that I don't believe cholesterol is  the serious heart risk factor that the drug companies make it out to be in their advertising. However, I also don't believe that it's healthy to let cholesterol go unchecked. As I've said before, research shows there is a healthy range for cholesterol. If you go too far above it or below it, you're asking for trouble.

Fortunately, reducing cholesterol is relatively easy and doesn't usually require medication. It just takes a little discipline, some patience, and a cholesterol lowering diet. To start, try the three nutritional recommendations below. If done daily, they will reduce your cholesterol level in about four weeks--even with no other changes to what you eat.

1) Eat a breakfast that includes a serving of oat bran, raisin bran, shredded wheat, or bran flakes with a fresh fruit such as blueberries, strawberries, raspberries, bananas, peaches, etc. Add two tablespoons of organic flaxseed, grind it up in a coffee grinder, and serve with 6-9 oz. of organic skim or 1% milk.

2) Eat one pear or one apple, and one medium-sized carrot.

3) For a snack, or as a dessert with any meal, eat one half of a grapefruit, including all of the white pulp. This is loaded with pectin, a soluble fiber. Please note, however, that there's a very important warning that goes along with this recommendation. You should only eat grapefruit (or drink grapefruit juice) after talking with your doctor to confirm that none of the medications you're taking will interact with it. The effects of many cardiovascular drugs, including statins, can be intensified when combined with grapefruit or grapefruit juice. This is because grapefruit affects enzyme systems in the liver and increases the amount of the drugs in your blood. So, if you're taking one of these drugs, I don't advise that you eat grapefruit or drink grapefruit juice. Just stick with the first two recommendations instead.

By eating these foods every day, you'll get 15-20 grams of fiber, which will help you achieve healthy cholesterol levels and bring you many other health benefits.

Lp(a): The Most Dangerous Form of Cholesterol

Thursday, March 5, 2009 by Stephen Sinatra
A few weeks ago, I posted some thoughts on why I don't believe that reducing cholesterol is the magic bullet that will prevent or cure heart disease. For starters, cardiovascular problems just aren't that simple, and on top of that, most cholesterol is completely harmless.

There is, however, one form of cholesterol that always requires aggressive treatment. It's called lipoprotein(a), or Lp(a), and it's one of the most dangerous heart risk factors.

Lp(a) is a subtype of LDL cholesterol that is highly inflammatory and thrombotic, which means it causes the blood to thicken and clot. Everyone has some Lp(a) in their blood stream--but when it increases abnormally, Lp(a) can raise your risk of having a heart attack up to 25 times.

Finding out if you have high Lp(a) is relatively simple. Just ask your doctor for one of the new-generation blood lipid tests that measure your cholesterol subtypes. There are two of them on the market, one called the Lipoprotein Particle Profile, or LPP, and another called the Vertical Auto Profile, or VAP. I prefer the LPP because I think the measurements are more precise, but both will tell you how much Lp(a) is circulating in your blood. As a general rule, you want your score to be less than 10 mg/dL.

Unfortunately, treating high Lp(a) is a little bit more complicated. One challenge is that there are no drugs with the ability to reduce it. Another is its genetic nature. High Lp(a) is often hereditary and is not the result of a poor diet or lack of exercise--which means you can't cure the problem through lifestyle changes, either.

That leaves just one genuinely good option, and that's to use natural therapies that offset the toxic effects of Lp(a) in the blood. Since Lp(a) causes inflammation and thickening of the blood, you want to look for products that have the opposite effect. I like fish oil (1-2 g daily) and nattokinase (50-100 mg daily). Fish oil is a natural blood thinner and has been shown to reduce inflammation, while nattokinase helps break down fibrin in the blood--one of the components that lead to clots. I also like high doses of vitamin C (1-2 g daily) for its antioxidant effects, as well as niacin (500 mg), which helps lower blood pressure.

Another option that I like is delta tocotrienol. Tocotrienol compounds occur naturally in plants and protect the carotenoids in plants from degradation. New research shows that delta tocotrienol is an effective means for reducing cholesterol overall, and it may be effective specifically on Lp(a). I recommend 100 mg daily.

Though it's somehwat less effective than targeted nutritional supplementation, you can also attack Lp(a) through a heart-healthy, cholesterol lowering diet. The PAMM eating plan (Pan Asian Modified Mediterranean) is a good place to start. It emphasizes healthy fats such as olive oil, along with whole grains, beans, legumes, nuts, fresh fruits and vegetables, and very small servings of meat (preferrably fresh, wild fish--not farm raised). This will help keep your ratio of HDL cholesterol to LDL cholesterol in proper balance, and the fresh fruits and legumes--such as chickpeas and lentils--indirectly help to reduce Lp(a) by lowering insulin levels.

Finally, there are certain people for whom an Lp(a) test is an absolute must. The first group includes anyone with a family history of heart disease. Lp(a)'s tendency to run in families means that these folks, above everyone else, need to find out if their levels are in the normal range. The test is alo essential if you're a postmenopausal woman or you have diabetes, because we know that Lp(a) increases in both of those groups. Women, it is hypothesized, experience elevated levels due to falling estrogen levels. This may be why the incidence of heart disease quadruples among menopausal women.
 
Of course, I urge the rest of you to have your Lp(a) level tested, too. The best way to prevent cardiovascular problems is to know your risk factors--and act accordingly.